The Fox Focus Fall/Winter 2016

REMEMBERING FALL/ W I N TER 2 0 16 MUHAMMAD ALI on page 14 FOCUS O N PA R K I N S O N ’ S Sowing the Seeds of Success: The Science of “De-Risking” Research New cause for optimism in the Parkinson’s pipeline by LOREN DeVITO, PhD Parkinson’s research is risky. As any scientist can tell you, most experiments never make it past the Petri dish. The journey of a potential new drug through multiple modes and phases of testing is a long and twisting one, with countless challenges along the way. Yet in spite of these odds, some ideas do ultimately succeed and become medicines that improve human health. The Michael J. Fox Foundation (MJFF) exists to “de-risk” the research process for the most promising new ideas in Parkinson’s disease (PD), so that more of them cross the finish line. We tackle roadblocks head-on, supporting early-stage testing where researchers need to generate data to build the case for their idea, and addressing systemic challenges that can help science move faster. And it’s working. Over the past several months, at an increasingly rapid pace, investments made by our Foundation at early stages of promising research have accelerated multiple compounds. Today, more potential new Parkinson’s drugs than ever before are pulling ahead on their journey Grand Central Station P.O. Box 4777 New York, NY 10163-4777 www.michaeljfox.org 800 708 7644 (continued on page 4) In This Issue 7 8 10 17 Fall/Winter 2016 Research Briefs MJFF’s Public Policy Priorities Dr. Dolhun Talks PD: New Therapies Draw for the 2016 Nike Mag Fall/Winter 2016 Photo by Mark Seliger THE FOX